Septo-Hippocampo-Septal Loop and Memory Formation

نویسندگان

  • Akram Eidi Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
  • Ali Haeri-Rohani Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
  • Fatemeh Khakpai Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
  • Mohammad Nasehi Department of Biology, Faculty of Basic Sciences, Islamic Azad University, Garmsar Branch, Semnan, Iran.
  • Mohammad Reza Zarrindast Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
چکیده مقاله:

The Cholinergic and GABAergic .bers of the medial septal/diagonal band of Broca (MS/DB) area project to the hippocampus and constitute the septo-hippocampal pathway, which has been proven to play a role in learning and memory. In addition, the hippocampus has bidirectional connections with the septum so that to self-regulate of cholinergic input. The activity of septal and hippocampal neurons is modulated by several neurotransmitter systems including glutamatergic neurons from the entorhinal cortex, serotonergic .bers from the raphe nucleus, dopaminergic neurons from the ventral tegmental area (VTA), histaminergic cells from the tuberomammillary nucleus and adrenergic .bers from the locus coeruleus (LC). Thus, changes in the glutamatergic, serotonergic and other systems- mediated transmission in the MS/DB may in.uence cholinergic or GABAergic transmission in the hippocampus.

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septo-hippocampo-septal loop and memory formation

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عنوان ژورنال

دوره 4  شماره 1

صفحات  5- 23

تاریخ انتشار 2013-02

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